双十八烷基二甲基溴化铵/DODMAB/DDAB,≥98% (TLC)
- 产品编号:D0120
- 中文名称:双十八烷基二甲基溴化铵/DODMAB/DDAB
- 英文别名:Dimethyldioctadecylammonium bromide
- CAS号:3700-67-2
- 分子式:(C18H37)2(CH3)2NBr
- 分子量:630.95
- 纯度:≥98% (TLC)
- EC号:223-037-6
- MDL号:MFCD00041975
订货信息:
产品规格价格(RMB)
- D0120-10G100
- D0120-50G260
- D0120-100G400
性能描述
性状:白色粉末
保存温度:室温保存
Dimethyldioctadecylammonium bromide is a tetraalkylammonium compound with long chain alkyl groups, which give it lipophilic properties. The alkyl groups of DDAB allow for its application in the preparation of cationic liposomes. Such liposomes may be used as DNA carrier systems for gene transfection and as vehicles for drug delivery.
DDAB bilayers have been utilized to study their effects on the molecular conformation of 2¢-deoxyadenosine 5¢-monophosphate by circular dichroism (CD) spectroscopy to probe the denaturation of DNA after complexing with cationic lipids.A CD study of the interaction of supercoiled plasmid DNA with DDAB has been reported.
DDAB is used in immunology as an adjuvant.It has been utilized to induce experimental arthritis in rats.9 An in vivo study of pseudorabies virus in pigs has indicated that application of a DNA vaccine in conjunction with DDAB caused stronger immune responses than application of the vaccine alone and generally led to enhanced antiviral immunity.
溶解性:This product is soluble in ethanol (100 mg/ml) with heat as needed.